Clomixin – 50mg/tab

Description

Farestos is a cutting-edge alternative to Clomid, boasting a host of beneficial properties that make it a superior choice in various applications.

Toremifene Citrate, a selective estrogen receptor modulator (SERM) derived from triphenylethylene, was patented and approved in Europe in the mid-1990s for the treatment of metastatic ER+ cancer in postmenopausal women.

In the realm of bodybuilding, toremifene citrate is utilized by men as a post-cycle therapy (PCT) drug to mitigate the effects of excessive estradiol resulting from the aromatization of androgens. Specifically, toremifene aids in restoring endogenous testosterone levels and preventing estrogen-related side effects such as gynecomastia.

It is important to note that as a SERM, toremifene citrate functions as a genuine estrogen blocker, distinguishing itself from aromatase inhibitors. By binding more strongly to estradiol receptors in various tissues, toremifene effectively blocks the activity of estradiol, preventing it from binding and activating these receptors. This mechanism ensures that estradiol is unable to exert its effects, as the receptors are already occupied by toremifene.

Important Note: Toremifene does not decrease the overall total circulating plasma levels of estradiol in the body; it simply blocks its activity in specific tissues. This sets it apart from aromatase inhibitors, which lower total circulating levels of estradiol by binding to the aromatase enzyme responsible for converting androgens into estradiol (aromatization).

While toremifene shares a similar chemical structure with tamoxifen, it is considered a newer generation drug with fewer toxic side effects.

However, there are some drawbacks to toremifene. One significant issue is its negative impact on SHBG (Hormone Binding Globulin) levels in the body. Clinical studies have shown that while toremifene can stimulate the natural production of testosterone, it actually raises SHBG levels. This can potentially reduce the effectiveness of a cycle when used to combat symptoms of gynecomastia.

In the realm of HPTA restoration and endogenous testosterone production in males, it has been established that toremifene is not as potent as tamoxifen when administered in equal doses. Research indicates that while toremifene, at a daily dose of 60mg, increased testosterone levels in test subjects by 42%, this increase is lower compared to a standard 20mg daily dose of tamoxifen in the same study, which raised testosterone levels by 71%.

For a more effective boost in testosterone production, it is recommended that toremifene dosage be increased to up to 120mg per day. This dosage can be maintained at 100mg/day for the second week of PCT, and then reduced to 60mg/day for the remaining 3 – 4 weeks of PCT. Individual dosages should be determined based on personal results.

There are no specific guidelines for toremifene administration. It can be taken before, during, or after meals, and can be consumed in the morning or at night before bed. There is no need to split up the dosage throughout the day, as toremifene has a half-life of approximately 5 days, which allows for stable levels over a 24-hour period without the need for multiple doses.